As filed with the Securities and Exchange Commission on August 12, 2024

 

Registration No. 333-   

 

 

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

 

Washington, D.C. 20549

 

FORM S-8

 

REGISTRATION STATEMENT

UNDER

THE SECURITIES ACT OF 1933

 

Astria Therapeutics, Inc.

(Exact Name of Registrant as Specified in Its Charter)

 

  Delaware   26-3687168  
  (State or Other Jurisdiction of
Incorporation or Organization)
  (I.R.S. Employer
Identification No.)
 

 

 

22 Boston Wharf Road, 10th Floor

Boston, Massachusetts

 

 

 

02210

 
  (Address of Principal Executive Offices)   (Zip Code)  

 

Second Amended and Restated 2015 Stock Incentive Plan

2015 Employee Stock Purchase Plan

2022 Inducement Stock Incentive Plan, as amended

(Full Title of the Plan)

 

Benjamin Harshbarger

Chief Legal Officer
22 Boston Wharf Road, 10th Floor
Boston, Massachusetts 02210

(Name and Address of Agent For Service)

 

(617) 349-1971

(Telephone Number, Including Area Code, of Agent For Service)

 

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer”, “smaller reporting company” and “emerging growth company” in Rule 12b-2 of the Exchange Act.

 

Large accelerated filer ¨ Accelerated filer ¨
Non-accelerated filer x Smaller reporting company x
    Emerging growth company ¨

 

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act. ¨

 

 

 

 

 

 

EXPLANATORY NOTE

 

This Registration Statement on Form S-8, relating to the Second Amended and Restated 2015 Stock Incentive Plan, the 2015 Employee Stock Purchase Plan and the 2022 Inducement Stock Incentive Plan, as amended, of Astria Therapeutics, Inc. (the “Registrant”), is being filed for the purpose of registering additional securities of the same class as other securities for which a Registration Statement on Form S-8 has previously been filed and is effective.

 

Accordingly, this Registration Statement incorporates by reference the contents of:

 

· the Registration Statement on Form S-8, File No. 333-206394, filed with the Securities and Exchange Commission (the “Commission”) on August 14, 2015, by the Registrant, relating to the Registrant’s Amended and Restated 2008 Equity Incentive Plan, as amended, 2015 Stock Incentive Plan and 2015 Employee Stock Purchase Plan;

 

· the Registration Statement on Form S-8, File No. 333-210229, filed with the Commission on March 16, 2016, by the Registrant, relating to the Registrant’s 2015 Stock Incentive Plan and 2015 Employee Stock Purchase Plan;

 

· the Registration Statement on Form S-8, File No. 333-216793, filed with the Commission on March 17, 2017, by the Registrant, relating to the Registrant’s 2015 Stock Incentive Plan and 2015 Employee Stock Purchase Plan;

 

· the Registration Statement on Form S-8, File No. 333-223721, filed with the Commission on March 16, 2018, by the Registrant, relating to the Registrant’s 2015 Stock Incentive Plan and 2015 Employee Stock Purchase Plan;

 

· the Registration Statement on Form S-8, File No. 333-229643, filed with the Commission on February 13, 2019, by the Registrant, relating to the Registrant’s Amended and Restated 2015 Stock Incentive Plan and 2015 Employee Stock Purchase Plan;

 

· the Registration Statement on Form S-8, File No. 333-239114, filed with the Commission on June 12, 2020, by the Registrant, relating to the Registrant’s Amended and Restated 2015 Stock Incentive Plan and 2015 Employee Stock Purchase Plan;

 

· the Registration Statement on Form S-8, File No. 333-258633, filed with the Commission on August 9, 2021, by the Registrant, relating to the Registrant’s Amended and Restated 2015 Stock Incentive Plan and 2015 Employee Stock Purchase Plan;

 

· the Registration Statement on Form S-8, File No. 333-263459, filed with the Commission on March 10, 2022, by the Registrant, relating to the Registrant’s Amended and Restated 2015 Stock Incentive Plan, 2015 Employee Stock Purchase Plan and 2022 Inducement Stock Incentive Plan; and

 

· the Registration Statement on Form S-8, File No. 333-273773, filed with the Commission on August 7, 2023, by the Registrant, relating to the Registrant’s Amended and Restated 2015 Stock Incentive Plan, 2015 Employee Stock Purchase Plan and 2022 Inducement Stock Incentive Plan.

 

 

 

 

PART II

INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

 

  Item 8. Exhibits.

 

The following exhibits are incorporated herein by reference:

 

EXHIBIT INDEX

 

        Incorporated by Reference      
 Exhibit
Number
  Description of Exhibit   Form   File
Number
  Date of Filing   Exhibit
Number
  Filed
Herewith
 
4.1   Restated Certificate of Incorporation of the Registrant, as amended   8-K   001-37467   June 6, 2023   3.2      
                           
4.2   Amended and Restated By-Laws of the Registrant   8-K   001-37467   June 6, 2023   3.1      
                           
5.1   Opinion of Wilmer Cutler Pickering Hale and Dorr LLP, counsel to the Registrant                   X  
                           
23.1   Consent of Wilmer Cutler Pickering Hale and Dorr LLP (included in Exhibit 5.1)                   X  
                           
23.2   Consent of Ernst & Young LLP, Independent Registered Public Accounting Firm                   X  
                           
24.1   Power of attorney (included on the signature pages of this registration statement)                   X  
                           
99.1   Second Amended and Restated 2015 Stock Incentive Plan   10-Q   001-37467   August 12, 2024   10.1      
                           
99.2   2015 Employee Stock Purchase Plan   10-Q   001-37467   May 12, 2022   10.7      
                           
99.3   2022 Inducement Stock Incentive Plan, as amended   8-K   001-37467   December 20, 2023   99.1      
                           
107   Filing Fee Table                   X  

 

 

 

 

SIGNATURES

 

Pursuant to the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the city of Boston, Commonwealth of Massachusetts, on this 12th day of August, 2024.

 

  ASTRIA THERAPEUTICS, INC.
     
  By: /s/ Jill C. Milne
    Jill C. Milne
    President and Chief Executive Officer

 

POWER OF ATTORNEY AND SIGNATURES

 

We, the undersigned officers and directors of Astria Therapeutics, Inc., hereby severally constitute and appoint Jill C. Milne, Benjamin Harshbarger and Noah C. Clauser, and each of them singly, our true and lawful attorneys with full power to them, and each of them singly, to sign for us and in our names in the capacities indicated below, the registration statement on Form S-8 filed herewith and any and all subsequent amendments to said registration statement, and generally to do all such things in our names and on our behalf in our capacities as officers and directors to enable Astria Therapeutics, Inc. to comply with the provisions of the Securities Act of 1933, as amended, and all requirements of the Securities and Exchange Commission, hereby ratifying and confirming our signatures as they may be signed by our said attorneys, or any of them, to said registration statement and any and all amendments thereto.

 

Pursuant to the requirements of the Securities Act of 1933, this registration statement has been signed by the following persons in the capacities and on the dates indicated.

 

Signature   Title   Date
         
/s/ Jill C. Milne  

President and Chief Executive Officer and Director

(Principal Executive Officer)

  August 12, 2024
Jill C. Milne      
         
/s/ Noah Clauser   Chief Financial Officer   August 12, 2024
Noah Clauser   (Principal Financial Officer and Principal Accounting Officer)    
         
/s/ Kenneth Bate   Chairman of the Board of Directors   August 12, 2024
Kenneth Bate        
         
/s/ Sunil Agarwal   Director   August 12, 2024
Sunil Agarwal        
         
/s/ Joanne Beck   Director   August 12, 2024
Joanne Beck        
         
/s/ Frederick P. Callori   Director   August 12, 2024
Frederick P. Callori        
         
/s/ Hugh Cole   Director   August 12, 2024
Hugh Cole        
         
/s/ Michael Kishbauch   Director   August 12, 2024
Michael Kishbauch        
         
/s/ Gregg Lapointe   Director   August 12, 2024
Gregg Lapointe        
         
/s/ Jonathan Violin   Director   August 12, 2024
Jonathan Violin        

 

 

 

Exhibit 5.1

 

 

 

August 12, 2024

 

Astria Therapeutics, Inc.
22 Boston Wharf Road, 10th Floor

Boston, Massachusetts 02210

 

Re: Registration Statement on Form S-8: Second Amended and Restated 2015 Stock Incentive Plan, 2015 Employee Stock Purchase Plan and 2022 Inducement Stock Incentive Plan, as amended

 

Ladies and Gentlemen:

 

We have assisted in the preparation of a Registration Statement on Form S-8 (the “Registration Statement”) to be filed with the Securities and Exchange Commission (the “Commission”) under the Securities Act of 1933, as amended (the “Securities Act”), relating to an aggregate of 6,756,078 shares of common stock, $0.001 par value per share (the “Shares”), of Astria Therapeutics, Inc., a Delaware corporation (the “Company”), issuable under the Company’s Second Amended and Restated 2015 Stock Incentive Plan, 2015 Employee Stock Purchase Plan and 2022 Inducement Stock Incentive Plan, as amended (collectively, the “Plans”).

 

We have examined the Certificate of Incorporation and By-Laws of the Company, each as amended and restated to date, and originals, or copies certified to our satisfaction, of all pertinent records of the meetings of the directors and stockholders of the Company, the Registration Statement and such other documents relating to the Company as we have deemed material for the purposes of this opinion.

 

In our examination of the foregoing documents, we have assumed the genuineness of all signatures, the authenticity of all documents submitted to us as originals, the conformity to original documents of all documents submitted to us as certified, photostatic or other copies, the authenticity of the originals of any such documents and the legal competence of all signatories to such documents.

 

We assume that the appropriate action will be taken, prior to the offer and sale of the Shares in accordance with the Plans, to register and qualify the Shares for sale under all applicable state securities or “blue sky” laws.

 

We express no opinion herein as to the laws of any state or jurisdiction other than the state laws of the Commonwealth of Massachusetts, the General Corporation Law of the State of Delaware and the federal laws of the United States of America.

 

It is understood that this opinion is to be used only in connection with the offer and sale of the Shares while the Registration Statement is in effect.

 

Please note that we are opining only as to the matters expressly set forth herein, and no opinion should be inferred as to any other matters.

 

 

 

 

 

Astria Therapeutics, Inc.

August 12, 2024

Page 2

 

Based on the foregoing, we are of the opinion that the Shares have been duly authorized for issuance and, when the Shares are issued and paid for in accordance with the terms and conditions of the applicable Plan, the Shares will be validly issued, fully paid and nonassessable.

 

We hereby consent to the filing of this opinion with the Commission in connection with the Registration Statement in accordance with the requirements of Item 601(b)(5) of Regulation S-K under the Securities Act. In giving such consent, we do not hereby admit that we are in the category of persons whose consent is required under Section 7 of the Securities Act or the rules and regulations of the Commission.

 

Very truly yours,

 

/s/ WILMER CUTLER PICKERING HALE AND DORR LLP  
WILMER CUTLER PICKERING HALE AND DORR LLP  

 

 

 

 

Exhibit 23.2

Consent of Independent Registered Public Accounting Firm

 

We consent to the incorporation by reference in the Registration Statement (Form S-8) pertaining to the Second Amended and Restated 2015 Stock Incentive Plan, the 2015 Employee Stock Purchase Plan and the 2022 Inducement Stock Incentive Plan, as amended, of Astria Therapeutics, Inc. of our report dated March 4, 2024, with respect to the consolidated financial statements of Astria Therapeutics, Inc. included in its Annual Report (Form 10-K) for the year ended December 31, 2023, filed with the Securities and Exchange Commission.

 

/s/ Ernst & Young LLP

 

Boston, Massachusetts

August 12, 2024

 

 

 

Exhibit 107

 

Calculation of Filing Fee Tables

 
Form S-8
(Form Type)
 
Astria Therapeutics, Inc.
(Exact Name of Registrant as Specified in its Charter)

 

Table 1—Newly Registered Securities

 

Security
Type
  Security
Class Title
  Fee
Calculation
Rule
  Amount
Registered
(1)
  Proposed
Maximum
Offering
Price Per
Share
  Proposed
Maximum
Aggregate
Offering
Price
  Fee Rate   Amount of
Registration
Fee
 
Equity(2)   Common Stock, $0.001 par value per share   Other(3)     6,756,078 shares(2)   $ 9.59 (3)  $ 64,790,788.02 (3)  $147.60 per
$1,000,000
  $ 9,563.12  
Total Offering Amounts                 $ 64,790,788.02       $ 9,563.12  
Total Fee Offsets                              
Net Fee Due                           $ 9,563.12  

 

(1) In accordance with Rule 416 under the Securities Act of 1933, as amended (the “Securities Act”), this Registration Statement shall be deemed to cover any additional securities that may from time to time be offered or issued to prevent dilution resulting from stock splits, stock dividends or similar transactions.

 

(2) Consists of (i) 5,750,000 shares issuable under the Second Amended and Restated 2015 Stock Incentive Plan, (ii) 6,078 shares issuable under the 2015 Employee Stock Purchase Plan, and (iii) 1,000,000 shares issuable under the 2022 Inducement Stock Incentive Plan, as amended.

 

(3) The proposed maximum offering price per share of $9.59 is estimated solely for the purpose of calculating the registration fee pursuant to Rules 457(c) and 457(h) under the Securities Act and is based upon the average of the high and low prices of the Registrant’s Common Stock as reported on the Nasdaq Global Market on August 5, 2024.